Sunderland, who have made a strong start under manager Regis Le Bris, are standing in Amorim's way. They are currently in the top five after six games, which is the best start to a Premier League campaign by a promoted side in over a decade.
The match offers several betting opportunities. Sunderland are expected to score, with a 57/100 chance of getting on the board, and over 1.5 goals are likely, with a 1/5 chance of more than one goal being scored.
One player to watch is Matheus Cunha, who has been one of Manchester United's most persistent attackers despite the team's struggles. He has had 3+ shots in four of his last five league starts and is expected to see plenty of the ball in advanced areas, making 2+ shots at 11/100 a likely outcome.
The odds for the match are Manchester United at 1/2, a draw at 15/4, and Sunderland at 19/4.
For those looking to take advantage of the Premier League matches for their bets, there are several promotions and bonus codes available on various betting sites.