The game is one of the biggest in the Premier League calendar, regardless of the teams' current form. Here are three key battles that could prove decisive in the match.
Patrick Dorgu vs Mohamed Salah
Chelsea left-back Marc Cucurella revealed that his team targeted Liverpool's Mohamed Salah during their previous match, knowing that the Egyptian's limited defensive contributions would leave right-back Conor Bradley isolated. As predicted, Salah stayed forward, and Cucurella capitalized on the opportunity to score.
United will employ a different formation, with two number tens rather than traditional wingers, which may limit their width. Patrick Dorgu is expected to provide the width United needs to isolate Liverpool's right back. The Dane has the pace and crossing ability to be a significant attacking threat.
Dorgu's increased attacking freedom may leave United's left-sided center-back with a lot to handle, but their back-three formation should provide cover, with the right wingback dropping deeper to help defend.
Salah has a history of scoring against Manchester United, finding the net in 10 of the last 11 meetings between the two teams.
Virgil van Dijk vs Benjamin Sesko
Virgil van Dijk has been one of the best defenders in the Premier League this season, winning 41 duels, 32 aerial duels at a 78% success rate, eight interceptions, and seven blocks in his seven appearances. His performance against Chelsea suggested he may not be as effective in one-on-one situations.
Benjamin Sesko, Manchester United's big Slovenian striker, is starting to find his footing at Old Trafford. He has scored two goals in his last two games, both from inside the six-yard box. Sesko's physicality and success in the air make him a handful for opposing defenders.
The Man United striker likes to play close to his marker, using his physicality to win duels, particularly in the air, winning 16 of his aerial duels. He also has a high number of fouls committed, demonstrating his willingness to win the ball back.
Manuel Ugarte/Casemiro vs Florian Wirtz
Florian Wirtz, Liverpool's German midfielder, has failed to score or provide an assist in a competitive game since joining the club. Despite this, his underlying numbers suggest he has been creating chances for his teammates. Wirtz has created 11 chances for Liverpool in the Premier League, generating an xG of 0.87.
Manchester United's midfield duo, including captain Bruno Fernandes, has been under scrutiny this season. Manager Ruben Amorim may choose to play either Casemiro or Manuel Ugarte, who was dropped for the previous international break.
The midfielders will need to cover a lot of space, as Fernandes will push higher up the field, leaving the midfield open for Liverpool to create. Wirtz will likely be under pressure, but this could be an opportunity for him to make a statement.
